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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC19A1
All Species:
7.27
Human Site:
T222
Identified Species:
16
UniProt:
P41440
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41440
NP_919231.1
591
64868
T222
D
D
R
G
R
C
E
T
S
A
S
E
L
E
R
Chimpanzee
Pan troglodytes
XP_001157360
590
64733
T222
D
D
R
G
R
C
E
T
S
A
S
E
L
E
R
Rhesus Macaque
Macaca mulatta
XP_001118114
475
51869
M130
E
F
F
Y
S
V
T
M
A
A
R
I
A
Y
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P41438
512
58132
V167
L
G
V
F
I
S
S
V
L
G
Q
A
L
V
T
Rat
Rattus norvegicus
Q62866
512
58076
V167
L
G
V
F
I
S
S
V
L
G
Q
V
L
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521689
430
48416
R85
F
S
L
V
S
P
S
R
Y
Q
R
M
A
S
Y
Chicken
Gallus gallus
NP_001006513
496
55568
S151
A
Y
S
S
Y
I
F
S
L
V
A
P
S
R
Y
Frog
Xenopus laevis
NP_001085999
531
60307
F186
V
A
Y
S
S
Y
I
F
S
L
V
S
P
T
N
Zebra Danio
Brachydanio rerio
XP_002662447
528
59393
S183
Y
Q
R
V
A
S
Y
S
R
S
S
V
L
M
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17766
410
46514
T65
L
I
P
M
F
I
L
T
D
I
L
R
Y
K
P
Sea Urchin
Strong. purpuratus
XP_791719
533
60255
P187
F
V
I
S
L
F
L
P
S
V
H
K
S
T
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
73.2
N.A.
N.A.
59.3
58.8
N.A.
47.3
53.4
51.4
52.1
N.A.
N.A.
N.A.
26.3
34.6
Protein Similarity:
100
99.1
74.7
N.A.
N.A.
68.5
68.1
N.A.
59
64.4
63.9
63.9
N.A.
N.A.
N.A.
40
51.4
P-Site Identity:
100
100
6.6
N.A.
N.A.
6.6
6.6
N.A.
0
0
6.6
20
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
20
N.A.
N.A.
6.6
6.6
N.A.
0
13.3
6.6
33.3
N.A.
N.A.
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
0
0
0
10
28
10
10
19
0
0
% A
% Cys:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
19
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
19
0
0
0
0
19
0
19
0
% E
% Phe:
19
10
10
19
10
10
10
10
0
0
0
0
0
0
0
% F
% Gly:
0
19
0
19
0
0
0
0
0
19
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
10
10
0
19
19
10
0
0
10
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
28
0
10
0
10
0
19
0
28
10
10
0
46
0
0
% L
% Met:
0
0
0
10
0
0
0
10
0
0
0
10
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
10
0
0
10
0
10
0
0
0
10
10
0
10
% P
% Gln:
0
10
0
0
0
0
0
0
0
10
19
0
0
0
0
% Q
% Arg:
0
0
28
0
19
0
0
10
10
0
19
10
0
10
19
% R
% Ser:
0
10
10
28
28
28
28
19
37
10
28
10
19
10
10
% S
% Thr:
0
0
0
0
0
0
10
28
0
0
0
0
0
19
19
% T
% Val:
10
10
19
19
0
10
0
19
0
19
10
19
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
10
10
10
10
10
0
10
0
0
0
10
10
28
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _